Is there a connection between creatine and DHT ?
Is there a connection between creatine and DHT ? The exact relationship between Creatine and DHT levels in the body has not been completely confirmed by research. Therefore, individuals interested in hair restoration strategies would need to use their own direction, preferably under the guidance and recommendations of a physician. However, it is still worth noting there is some indication that creatine supplement can increase the conversion rate of testosterone to DHT (dehydrotestosterone which is a more active type of androgen). This process takes place in the liver, through the action of an enzyme known as 5-alpha-reductase. Here are brief details about a small study that was done.

According to a three week research study which involved a small sample size of 20 male rugby players, the levels of DHT increased after the participants were given 25mg of creatine per day. After 7 days, DHT levels increased by 56% and remained 40% above baseline during the following 14 days of maintenance. The ratio of testosterone to DHT also increased. This was measured at 36% after 7 days. And during the 14 days, these ratio levels remained elevated by 22%.

Since this study was done one such a small sample size, it is not possible to generalize these findings to larger populations at this time until further research is performed.

Is there a connection between creatine and DHT ? What is Creatine?

While creatine is being discussed in forums and social sites for those who want to restore their hair, it may be helpful to understand what it is outside this context.

Due to its chemical structure, creatine is classified as an acid compound. It is made of three types of amino acids: L-arginine, glycine, and L-methionine.

Like DHT, it is also produced in the liver. Creatine’s main role is to supply energy to various cells in the body, mainly the skeletal muscles. It also supplies energy to the brain as well. But 95% of the creatine in our body is stored in the muscles.

The most desirable trait of this compound is it’s ability to quickly produce supply energy to locations in the body which demand it. Therefore, it is of particular interest to athletes.

Creatine is not only produced by the body, but is also available as a supplement. It’s usage has been approved by: the NCAA (National Collegiate Athletic Association) and the International Olympic Committee.

How DHT Affects Hair Loss and Restoration Efforts

It is important to remember that DHT itself is not the cause of androgenic alopecia. The main culprit is genetic predisposition. Coding in the DNA will create structural deviations in the androgen protein receptors at the base of the follicles. Therefore, those with the genes for pattern baldness will have less resilience to the unwanted effects of DHT (namely, hair loss and thinning). In those who are susceptible, DHT will interfere with the absorption of nutrients from capillaries around the hair follicle. And this is what causes miniaturization to occur.

Those who are not genetically predisposed to pattern baldness will not have to worry about restoring hair, if their DHT levels are high.

Male Pattern Baldness and DHT
DHT is known to be involved in the main pathway that causes male pattern baldness*

Body Hair Transplant For Body Builders Taking Androgen Supplements

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